On the eve of Judgement Day, predatory cannibals abduct two young vagabond women harboring a shocking secret - they are ancient Vampires. Following a bloody clash, the Vampires are suddenly confronted with an apocalyptic crisis as soul-stealing alien creatures invade and attack humanity, turning their victims into flesh eating Zombies. The forces of evil collide in a cataclysmic battle for dominance.

Set in a post-apocalyptic world where a global airborne pandemic has wiped out 90% of the Earth's population and only the young and immune have endured as scavengers. For Ellie and Quinn, the daily challenges to stay alive are compounded when they become hunted by the merciless Stalkers.